“Vascular Endothelium: A Dynamically Mutable Interface”
The Foundations and Future of Vascular Biology

Saturday, June 11th, 2011  

Joseph B. Martin Conference Center
Harvard Medical School

SCIENTIFIC PROGRAM       

8:00 a.m.CHECK-IN AND BREAKFAST
8:45 a.m.Welcoming Remarks: Guillermo García-Cardeña
8:50 a.m.Opening Remarks: Elizabeth G. Nabel

SESSION 1: VASCULAR ENDOTHELIUM IN HEALTH AND DISEASE
Chair: Peter Libby

9:05 a.m.R. Wayne Alexander. Endothelial dysfunction and vascular disease.
9:30 a.m.Charles N. Serhan. Novel mediators and mechanisms in the resolution of acute inflammation.
9:55 a.m.Shaun Coughlin. Protease signaling in vascular biology and beyond...
10:20 a.m.Salvador Moncada. Stepping stones in endothelial research ... the making of an organ.
10:45 a.m.COFFEE BREAK

SESSION 2: ENDOTHELIAL CELL ACTIVATION AND ADHESION BIOLOGY
Chair: Jordan S. Pober

11:05 a.m.Jordan S. Pober. Endothelial activation and inflammation.
11:30 a.m.Myron Cybulsky. Adhesion molecules, leukocytes and atherosclerosis.
11:55 a.m.Tanya Mayadas. cAMP dependent mechanisms of endothelial barrier function.
12:20 p.m.Masayuki Yoshida. Adhesion molecules: reliable guide of vascular inflammation.
12:45 p.m.LUNCH

SESSION 3: VASCULAR ENDOTHELIUM AND INFLAMMATION
Chair: F. William Luscinskas

1:35 p.m.F. William Luscinskas. Gatekeepers of leukocyte recruitment: CD47 rolls, arrests and transmigrates.
2:00 p.m.William Muller. The role of the endothelium in leukocyte transendothelial migration: even more dynamic than we thought!
2:25 p.m.Peter Libby. Inflammation in atherosclerosis- from the petri plate to patients and populations.
2:50 p.m.Paul Ridker. The cardiovascular inflammation reduction trials: 30 years from IL-1 to CANTOS.

SESSION 4: BIOMECHANICAL FORCES AND CARDIOVASCULAR BIOLOGY
Chair: Forbes Dewey

3:20 p.m.Forbes Dewey. Stressed out for 30 years.
3:45 p.m.Peter F. Davies. Shear inspiration!
4:10 p.m.Natacha DePaola. Vascular endothelium responds to fluid shear stress gradients.
4:35 p.m.Frederick Schoen. Heart valve dynamics: on the cusp of understanding mechanisms of function and disease.
5:00 p.m.Guillermo García-Cardeña. Biomechanical control of endothelial cell fates.
5:30 p.m.Closing Remarks: Michael A Gimbrone Jr.
5:45 p.m.RECEPTION